Darkseid (voiced by Michael Ironside) is the absolute ruler of Apokolips, would-be conqueror of the universe and Superman's and The Ed's greatest enemy.
He psychically feeds on the despair and misery of others. Darkseid has conquered and subjugated an unspecified number of planets throughout the universe. Darkseid has only three goals: to conquer Earth, & destroy the Justice League, & find & acquire the "Anti-Life Equation". He was defeated by Lex Luthor, when he gave him The Anti-Life Equation, taking them both when the equation was activated.
- Darkseid is the ultimate enemy of Darkblade and The Eds. He is the new ruler of The Horde Of Darkness.
- Darkseid will become one of Jaden and Jeffrey's dangerous enemies in the future.
- Darkseid will become Aaron's most terrifying enemy in the future.
- Will join "The Legion of Darkness."
- Darkseid will become Twilight and the Rainbooms' enemy in Twilight and The Rainbooms meets Justice League, and after he learned that they have Equestrian magic within them, he seeks to obtain their magic and seal their fate.
- Darkseid will be defeated and publicly humiliated by Kyle Akers after Kyle unlocks his true power of righteousness.