Dr. Cockroach, Ph.D. (Vocied by Hugh Laurie) is a brilliant mad scientist with his result of an experiment going wrong in Monsters vs. Aliens. He can withstand being crushed, smashed, blow'n up & eletracutied as well as climb up walls & cellings.
- Jeffrey will meet Dr. Cockroach in Jeffrey & Friends' Adventures of Monsters vs. Aliens.
- Dr. Cockroach will attend Jeffrey and Aqua's wedding in Key of Flaming Union.
- Dr. Cockroach will guest star in Jeffrey, Jaden & Friends' Storm Adventures of Stitch!: The Movie.