Knuckles' name is derived from the four knuckles, two on each hand, which are actually sharp spikes. According to official Sonic Team polls, Knuckles is the fourth most popular character in the series, behind Tails, Shadow and Sonic.
His first game appearance was in Sonic the Hedgehog 3, released on February 2, 1994 for the Sega Mega Drive/Genesis. He was described as being 15 years old when he made his debut, but since Sonic Adventure, he is now given the age of 16. Knuckles has two spikes on each hand, and his dominant trait is his strength and that can be used to dig. He can also glide by trapping air under his dreadlocks, can climb up walls with ease, and is very skilled at a wide variety of martial art forms.
- Knuckles will guest star in Jeffrey, Jaden & Friends' Storm Adventures of Foster's Home for Imaginary Friends: Destination Imagination.
- Knuckles will appear again in Jaden meets Inspector Gadget.
- Knuckles meets Juniper Lee during a brief cameo in the eighth episode of Juniper Lee's Adventures Series titled Super Smash Sister.