Ratigan (voiced by the late Vincent Price) is the main antagonist of The Great Mouse Detective. He's a evil sewer rat who is a powerful criminal. Basil himself called Ratigan, "The Napoleon of Crime", seeing as how he's known The World's Greatest Criminal Mind.
Personality-wise, Ratigan is very charismatic, calm and calculating, but can easily be sent into a violent rage at the mention of his enemy Basil or the incompetence of his minions. He has a very dark, malicious sense of humor and a inflated ego.
Even though he IS one, Ratigan hates being called a rat.
- Ratigan will become Jeffrey's enemy in Jeffrey & Friends' Adventures of The Great Mouse Detective.
- Ratigan will return for revenge in Jeffrey & Friends discover A Troll in Central Park.
- Ratigan will return for revenge again in Jeffrey & Friends get Flushed Away.
- Ratigan will return for revenge in Jeffrey, Jaden & Friends' Storm Adventures of Muppets Most Wanted.
- Ratigan will become Sly Cooper's enemy in Sly Cooper meets The Great Mouse Detective.
- Ratigan will become Aaron's enemy in Aaron meets The Great Mouse Detective.
- Ratigan will become Arik's enemy in Arik Meets The Great Mouse Detective.
- Vincent Price's favorite role in his acting carrer was Professor Ratigan, because he was given two original songs made just for his character. The first being "Goodbye So Soon." And The Second being the most famous, "The World's Greatest Criminal Mind."